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Method to identify antibody targets NICOLETTE CHARLES A

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Publications Authored by Charles A Nicolette | PubFac

Charles A Nicolette UNVERIFIED PROFILE Are you Charles A Nicolette? Register this Author Register author Register with ORCID iD PUBLICATIONS 16 ...

Metagenomic Sequencing Identifies a Clinical Pathogen that Other Technologies Miss

set of targets, metagenomic sequencing doesn’t target individual genes or pathogens. Instead, it enables interrogation ... it initially came back negative by antibody testing and the gold standard PCR for Leptospira. We later showed that the reason the CDC PCR ...

A high-throughput proteo-genomics method to identify antibody targets associated with malignant disease - ScienceDire

A high-throughput proteo-genomics method to identify antibody targets associated with malignant disease Author links open overlay panel Yinyin Huang Joseph Franklin Kathreen Gifford Bruce L Roberts Charles A Nicolette Show more https://doi.org/10.1016/j ...

Imaging protein synthesis in cells and tissues with an alkyne analog of puromyc

We introduce a simple and robust chemical method to image and affinity-purify nascent proteins in cells and in animals, based on an alkyne analog of puromycin, O ...

A handheld platform for target protein detection and quantification using disposable nanopore strips | Scientific Repor

low-energy instrumentation requirements. While nanopore sensors have demonstrated efficacy for nucleic acid targets, ... The scaffold-to-antibody coupling method can be applied to any available antibody or antibody fragment since it utilizes lysines A ...

Title of report: Publishable Report - European Commission : CORDIS : Ho

5 To investigate prognostic value of proteins like L1 or vitamin E-binding protein as alternatives to the standard serum tumour marker CA125 and their potential as targets for antibody-based therapy To identify accessible and antigenic sites on ovarian cancer ...

Patents by Inventor Bruce L Rober

Abstract: The invention provides methods of treating lupus in a patient with an anti-CD52 antibody. ... and to a method of preparing a humanized immunoglobulin. The humanized immunoglobulins can be used in therapeutic applications to treat, for example ...

Research works produced by Charles A Nicolette | Genzyme Corporation, Massachusetts and other plac

9 research works produced by Charles A Nicolette with 134 citations, including: A high-throughput proteo-genomics method to identify antibody targets associated with malignant disease ... Cytomegalovirus (CMV) infection is a serious complication of allogeneic ...

Annemarie Nicolette Lekkerkerker Inventions, Patents and Patent Applications - Justia Patents Sear

Abstract: The present invention relates to methods and assays for identifying agents useful in the treatment of fibrotic conditions. The invention provides polypeptide and nucleic acid TARGETs, siRNA sequences based on these TARGETs and antibodies against the ...

Expanding the Circuitry of Pluripotency by Selective Isolation of Chromatin-Associated Protei

novel method to identify chromatin-bound proteins that colocalize with a bait protein on DNA. Applied to Oct4, Sox2, ... tions, in that it targets endogenous proteins, does not require protein tagging or overexpression, uses formaldehyde for including removal of ...

Serum antibody repertoire analysis for high-throughput epitope discovery and characterizati

sequences of antibody-binding peptides can be determined and used to identify the original antibody targets, ... AMD progression.Additional methods were developed to improve the discovery and characterization of epitopes from the antibody repertoire ...

Staufen2 Regulates Neuronal Target RNAs: Cell Repor

with the effect of downregulation on those targets (to identify the role of Stau2 in posttranscriptional regulation ... (E17) hippocampal neurons were isolated from embryos of timed pregnant Sprague-Dawley rats (Charles River Laboratories) as Xie Y . ...

METHOD TO IDENTIFY ANTIBODY TARGETS BASED ON MASS SPECTROMETRY (MALDI-TOF) - Patent - Europe P

METHOD TO IDENTIFY ANTIBODY TARGETS BASED ON MASS SPECTROMETRY (MALDI-TOF) (PAT - EP1332371) NICOLETTE Charles A., ROBERTS Bruce L. GENZYME CORPORATION Patent: Publ. of Application without search report - European on ...

Monoclonal Antibodies | ProSp

Tumor cells that are able to replicate endlessly are fused with mammalian cells that produce a specific antibody which result in fusion called hybridoma that ...

Joseph Franklin's research works | Genzyme Corporation, Massachusetts and other plac

A high-throughput proteo-genomics method to identify antibody targets associated with malignant disease Joseph Franklin's research while affiliated with Genzyme Corporation and other places Publication (1) Source A high-throughput proteo ...

De novo transcriptome assembly and analysis to identify potential gene targets for RNAi-mediated control of the tomato leafminer ( Tuta absoluta .

this approach has emerged as a potential method to control agricultural pests by engineering plants to express insect dsRNAs. ... De novo transcriptome assembly and analysis to identify potential gene targets for RNAi-mediated control of the tomato) 1, ...

Antibody therapies for the prevention and treatment of viral infections | npj Vaccin

above-mentioned approach is not suitable for identification of novel neutralizing targets. To identify novel target ... V. & Sasisekharan, R. Broadly neutralizing influenza hemagglutinin stem-specific antibody CR8020 targets residues that are prone to escape ...

MART-1 compounds for therapy and diagnosis and methods for using same - NICOLETTE CHARLES

The present invention provides methods and compositions for detecting, diagnosing, prognosing and monitoring the progress of MART-1-related cancers and malignancies and kits for use in said methods. Further provided are methods for screening to identify ...

Method to identify antibody targets - Patent - Europe P

Method to identify antibody targets (PAT - US2002094530) NICOLETTE CHARLES A , ROBERTS BRUCE L Patent: Patent Appl. Publ. within the TVPP - United States Application: US20010955656 on 2001-09-18 Publication: 2002-07-18 Abstract The present ...

Lectin - Wikiped

A lectin from Dolichos biflorus is used to identify cells that belong to the A1 blood group. ... In neuroscience, the anterograde labeling method is used to trace the path of efferent axons with PHA-L, a lectin from the kidney bean. A lectin from bananas inhibits . ...